Inside this Issue
Ultra-processed foods increase your cancer risk - (01/04/26)
Does Artificial Intelligence have a role in prostate cancer? - (01/02/26)
What is the anti-cancer potential of green tea? - (01/07/26)
Probiotics may help with chemotherapy-induced diarrhea - (01/03/26)
Keep your cruciferous vegetables COLD! - (01/03/26)
2026: The Most Important Papers 01/01 - 01/07
(1 minute read)
As I read through this paper, what stood out to me was how consistent the evidence has become. The authors reviewed research published between 2018 and 2025, pulling from large population studies, meta-analyses (strong, valid research) and biological research from multiple countries. Across these studies, the pattern was obvious: people who eat more ultra-processed foods have a higher overall risk of developing cancer. The strongest and most consistent links were seen with colorectal, prostate, breast, and ovarian cancers.
What I found especially concerning is how measurable this risk appears to be. On average, every 10% increase in calories coming from ultra-processed foods was associated with a 10–12% higher cancer risk, and this is even after accounting for factors like body weight and physical activity. The paper also explains why this may be happening, pointing to several overlapping mechanisms: chronic inflammation, metabolic issues, chemicals from food additives and packaging, cancer-promoting compounds formed during processing and changes to your gut microbiome. When you consider how common ultra-processed foods have become, it’s clear why the authors describe this as a serious public health issue.
EVERYTHING IN MODERATION
What matters most isn’t one “bad” food, it’s how often ultra-processed foods show up. These foods are designed to be overeaten. They are deliberately “cravable” with fat, sugar and salt.
Ultra-processed foods include things like processed meats, sugary drinks, packaged snacks and ready-to-eat meals. They’re strongly linked to weight gain, chronic inflammation, hormone disruption and gut problems.
A simple rule I come back to again and again: eat foods that still look like food. It may sound dumb, but If it resembles something you could recognize or prepare at home, you’re usually on the right track.
When choosing meals or snacks, I encourage people to pair protein and fiber whenever possible. Think eggs, nuts, yogurt, beans, fruit, vegetables or even last night’s leftovers.
Try to limit foods with long ingredient lists, added sugars, or highly “engineered” textures that don’t exist in nature.
Small, consistent choices matter. What you grab at work, on the road or late at night adds up over time. But doing so can lower your cancer risk, or increase your survival.
(1 minute read)

AI for Prostate Cancer.
Is artificial intelligence actually ready to help guide real-world prostate cancer care? This paper looked at 15 different studies using AI to analyze genomic biomarkers (measurable changes in DNA or RNA that can signal how a cancer behaves). What impressed me is that these AI tools can sift through enormous amounts of genetic data and identify cancer-related genes that traditional methods often miss, including genes linked to aggressive disease, cancer spread, recurrence after surgery, survival and PSA progression.
I was also struck by how far this technology has already come. Some AI models were able to estimate how likely a patient might be to respond to certain treatments, such as hormone therapy or immunotherapy, and even predict the risk of side effects after radiation. That said, the authors are very clear (and I agree with them): this technology isn’t quite ready for everyday clinical use yet. Most of these AI models still need larger, real-world validation and proof that they truly improve outcomes for patients. For now, AI in genomic testing is promising, but it’s still a tool in development rather than something patients should rely on today.
HAS AI ARRIVED FOR PCa?
AI is getting very good at analyzing genetic information in prostate cancer, but today it’s still a research tool, not a standard medical test.
What this means for patients: AI may soon help doctors better answer questions like “How aggressive is my cancer?” or “Which treatments are most likely to work for me?” But most of these tools are not yet ready for routine care.
For now, I recommend continuing to rely on what we know works: PSA trends over time, biopsy results, imaging (MRI, PSMA PET when appropriate) and established genomic tests that are already validated and widely used.
(1 minute read)
I’m always cautious about health claims, especially when something sounds too simple to really matter. But green tea keeps showing up in the research over and over, so there’s got to be something to it. I have studied green tea. A lot!
A large scientific review looked at decades of studies on green tea and its natural compounds, particularly one called EGCG. What stood out to me is how consistently green tea appears to support the body’s natural defenses: decreasing chronic inflammation, reducing oxidative stress and helping damaged cells behave more normally. These are the same biological processes that are linked to cancer, heart disease, diabetes and other chronic conditions.
Across multiple studies, regular green tea consumption has been associated with lower risk or slower progression of cancers like prostate, breast, lung and colorectal cancer. It’s not a cure, and it’s not a replacement for medical care, but it’s a gentle, supportive habit that may help your body function like it’s supposed to.
GIVE GREEN TEA A TRY!
You don’t need supplements or extreme changes to benefit from this research:
Drink green tea regularly: ideally 2–5 cups per day, spread throughout the day rather than all at once.
Choose brewed green tea over sugary bottled teas, which often contain minimal catechins. Please try to avoid sugary drinks as much as possible. Sugar feeds growing cancers.
Be consistent: the protective effects appear over time, not overnight.
Don’t view green tea as a treatment, but as a supportive lifestyle habit that may reduce risk and support overall health alongside good nutrition, movement, and medical care.
I drink coffee and green tea daily. Both support your health with different antioxidants.
(1 minute read)
As I read this meta-analysis (strong research), I was encouraged by what it found for patients going through chemotherapy. The authors reviewed 15 high-quality randomized controlled trials involving nearly 1,500 adult cancer patients to see whether probiotics could help reduce chemotherapy-associated diarrhea. What stood out is that probiotics did, in fact, significantly lower the overall risk of diarrhea, with the strongest effect seen in severe cases. In those patients, the risk of severe, treatment-disrupting diarrhea was reduced by about 70%. Probiotics also helped reduce constipation, though they didn’t consistently improve other side effects like nausea, low white blood cell counts or low platelets.
One important nuance the paper highlights is that the benefits were more pronounced in Asian populations, while results in European and North American populations were weaker or more inconsistent. Even so, the findings were remarkably consistent in pointing to probiotics as a useful supportive tool during chemotherapy. To me, this reinforces the idea that while probiotics aren’t a cure or a replacement for medical treatment, they may play a meaningful role in helping patients tolerate therapy better and stay on track with their care.
MY TAKE ON PROBIOTICS DURING CHEMO
If you or someone you care for is going through chemotherapy and struggling with diarrhea, probiotics may help reduce the risk of severe symptoms that can interfere with treatment.
The research supports using live probiotic supplements instead of just “digestive support” drinks or foods.
I always recommend discussing probiotics with the oncology team first, especially during active cancer treatment.
When appropriate, look for a reputable probiotic that contains well-studied strains like Lactobacillus or Bifidobacterium.
Probiotics are typically taken daily during chemotherapy, and consistency matters more than high doses.
Stop probiotics and contact the care team if fever, signs of infection or immune complications develop.
[Editor’s Note: Sorry. Not every research paper is sexy 😆]
(1 minute read)
When I read this study, it really changed how I think about something as simple as storing vegetables. The researchers looked at kale, broccoli, and other cruciferous vegetables and showed that how we store them has a real impact on both shelf life and nutritional value. Using advanced techniques, they were able to explain why vegetables break down the way they do. At room temperature, these vegetables lost commercial quality in just three days, showing yellowing, wilting, and a noticeable drop in key nutrients.
What stood out to me is how powerful cold storage was. Storing these vegetables at 32°F did the best overall job of preserving vitamin C, chlorophyll (that vibrant green color), β-carotene, and total antioxidants than standard refrigerator temperatures around 41°F. That colder temperature actually “turned down” genes involved in breaking down pigments and nutrients, slowing the aging process of the vegetables themselves. Interestingly, storage at 41°F still had value, especially for preserving sulfur-containing compounds that are unique to cruciferous vegetables. This was a reminder that small choices like keeping greens colder and using them sooner, can make a meaningful difference in the nutrition we actually get from our food.
RULES FOR YOUR VEGGIES
Get it cold fast: Refrigerate as soon as you get home. Room temp = rapid yellowing/wilting.
Aim for the coldest zone: Store in the back/bottom of the fridge (most stable, coldest area), not the door .
Control moisture (don’t drown it): Keep it dry and add a paper towel in the bag to absorb condensation; swap if it gets wet.
Bag it loosely: Use a produce bag or loosely closed plastic bag to reduce water loss while still allowing a little airflow.
Use it in 3–5 days for peak nutrition: If you want the best green color & vitamin C & carotenoids, eat it sooner rather than later.
OTHER NEWS
You may have noticed that I sometimes abbreviate prostate cancer as PCa. I don’t need to be reminded of it and prefer this abbreviation. I think you might prefer it as well. You will see this more and more in future issues of Prostate 180.
There is so much more to share with you than just the most recent scientific research. Once I figure out a way to add other sections to this newsletter, I will let you know!
Thank you for checking in with me. We are here for each other 🙂





